The human G protein β4 subunit: gene structure, expression, Gγ and effector interaction
作者： Dieter Rosskopf , Christiane Nikula , Iris Manthey , Markus Joisten , Ulrich Frey
DOI: 10.1016/S0014-5793(03)00441-1
关键词:
摘要: The aim of this study was the characterization human Gβ4 subunit heterotrimeric G proteins. Human is widely expressed. Its gene located on chromosome 3 with a genomic structure indistinguishable from that genes Gβ1 to Gβ3, but entirely different Gβ5. In vitro translation co-precipitation analyses revealed can form stable dimers Gγ1, Gγ2, Gγ3, Gγ4, Gγ5, Gγ7, Gγ10, Gγ11, Gγ12, and Gγ13, which were also able stimulate phospholipase β2.
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