Mechanistic basis for inflammation and tumor promotion in lungs of 2,6-di-tert-butyl-4-methylphenol-treated mice: electrophilic metabolites alkylate and inactivate antioxidant enzymes.
作者： Brent W. Meier , Jose D. Gomez , Oleg V. Kirichenko , John A. Thompson
DOI: 10.1021/TX060214F
关键词:
摘要: … with promotion susceptibility in several inbred strains of mice. An … Brilliant Blue R250 in 40% methanol/10% acetic acid overnight … The functions of selenium binding protein are not fully …
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MM Bradford, None, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Analytical Biochemistry. ,vol. 72, pp. 248- 254 ,(1976) , 10.1016/0003-2697(76)90527-3
Hee-Jeong Choi, Sang Won Kang, Chul-Hak Yang, Sue Goo Rhee, Seong-Eon Ryu, Crystal structure of a novel human peroxidase enzyme at 2.0 Å resolution Nature Structural & Molecular Biology. ,vol. 5, pp. 400- 406 ,(1998) , 10.1038/NSB0598-400
Y. Manevich, S. I. Feinstein, A. B. Fisher, Activation of the antioxidant enzyme 1-CYS peroxiredoxin requires glutathionylation mediated by heterodimerization with πGST Proceedings of the National Academy of Sciences of the United States of America. ,vol. 101, pp. 3780- 3785 ,(2004) , 10.1073/PNAS.0400181101
Ruiyin Chu, Hanjo Lim, Laura Brumfield, Hong Liu, Chris Herring, Peter Ulintz, Janardan K. Reddy, Matthew Davison, Protein profiling of mouse livers with peroxisome proliferator-activated receptor α activation Molecular and Cellular Biology. ,vol. 24, pp. 6288- 6297 ,(2004) , 10.1128/MCB.24.14.6288-6297.2004
Zachary A Wood, Ewald Schröder, J Robin Harris, Leslie B Poole, Structure, mechanism and regulation of peroxiredoxins Trends in Biochemical Sciences. ,vol. 28, pp. 32- 40 ,(2003) , 10.1016/S0968-0004(02)00003-8
Judy L Bolton, Sherri B Turnipseed, John A Thompson, Influence of quinone methide reactivity on the alkylation of thiol and amino groups in proteins: studies utilizing amino acid and peptide models. Chemico-Biological Interactions. ,vol. 107, pp. 185- 200 ,(1997) , 10.1016/S0009-2797(97)00079-3
Henry C. Pitot, Fundamentals of Oncology ,(1978)
A. M. Malkinson, W. A. Evans, M. F. W. Festing, K. M. Koski, Butylated hydroxytoluene exposure is necessary to induce lung tumors in BALB mice treated with 3-methylcholanthrene. Cancer Research. ,vol. 57, pp. 2832- 2834 ,(1997)
Judy L. Bolton, J. A. Thompson, Oxidation of butylated hydroxytoluene to toxic metabolites. Factors influencing hydroxylation and quinone methide formation by hepatic and pulmonary microsomes. Drug Metabolism and Disposition. ,vol. 19, pp. 467- 472 ,(1991)
Alyson E. MITCHELL, Dexter MORIN, Jeffrey LAKRITZ, A. Daniel JONES, Quantitative profiling of tissue- and gender-related expression of glutathione S-transferase isoenzymes in the mouse. Biochemical Journal. ,vol. 325, pp. 207- 216 ,(1997) , 10.1042/BJ3250207