Evaluation of Left Ventricular Diastolic Dysfunction with Early Systolic Dysfunction Using Two-Dimensional Speckle Tracking Echocardiography in Canine Heart Failure Model.

作者: Wei-Chun Wu , Hong Ma , Rong-Ai Xie , Li-Jian Gao , Yue Tang

DOI: 10.1111/ECHO.13133

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摘要: Background This study evaluated the role of two-dimensional speckle tracking echocardiography (2DSTE) for predicting left ventricular (LV) diastolic dysfunction in pacing-induced canine heart failure. Methods Pacing systems were implanted 8 adult mongrel dogs, and continuous rapid right pacing (RVP, 240 beats/min) was maintained 2 weeks. The obtained measurements from 2DSTE included global strain rate during early diastole (SRe) late (SRa) longitudinal (L-SRe, L-SRa), circumferential (C-SRe, C-SRa), radial directions (R-SRe, R-SRa). Changes morphology observed by light microscopy transmission electron at weeks. Results The onset LV with systolic occurred 3 days after RVP initiation. Most imaging indices altered 1 or continued to worsen until failure developed. Light showed myocardial vacuolar degeneration mitochondrial swelling weeks onset. Pearson's correlation analysis revealed that parameters conventional moderate pressure parameters, including (r = 0.58, P < 0.01), L-SRe −0.58, E/L-SRe 0.65, R-SRe 0.53, 0.01). ROC curves these could effectively predict (area under curve: 0.78; 0.84; 0.80; 0.80). Conclusion 2DSTE a sensitive accurate technique be used model.

参考文章(39)
Yu Ting Tan, Frauke Wenzelburger, Eveline Lee, Grant Heatlie, Francisco Leyva, Kiran Patel, Michael Frenneaux, John E. Sanderson, The Pathophysiology of Heart Failure With Normal Ejection Fraction: Exercise Echocardiography Reveals Complex Abnormalities of Both Systolic and Diastolic Ventricular Function Involving Torsion, Untwist, and Longitudinal Motion Journal of the American College of Cardiology. ,vol. 54, pp. 36- 46 ,(2009) , 10.1016/J.JACC.2009.03.037
Koichi Kimura, Katsu Takenaka, Aya Ebihara, Tomoko Okano, Kansei Uno, Nobuaki Fukuda, Jiro Ando, Hideo Fujita, Hiroyuki Morita, Yutaka Yatomi, Ryozo Nagai, Speckle tracking global strain rate E/E' predicts LV filling pressure more accurately than traditional tissue Doppler E/E'. Echocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniques. ,vol. 29, pp. 404- 410 ,(2012) , 10.1111/J.1540-8175.2011.01587.X
Hisham Dokainish, Ranjita Sengupta, Manu Pillai, Jaromir Bobek, Nasser Lakkis, Usefulness of New Diastolic Strain and Strain Rate Indexes for the Estimation of Left Ventricular Filling Pressure The American Journal of Cardiology. ,vol. 101, pp. 1504- 1509 ,(2008) , 10.1016/J.AMJCARD.2008.01.037
Ryohei Suzuki, Hirotaka Matsumoto, Takahiro Teshima, Hidekazu Koyama, Influence of heart rate on myocardial function using two-dimensional speckle-tracking echocardiography in healthy dogs. Journal of Veterinary Cardiology. ,vol. 15, pp. 139- 146 ,(2013) , 10.1016/J.JVC.2012.12.004
Wojciech Kosmala, Rafal Plaksej, Joerg M. Strotmann, Carla Weigel, Sebastian Herrmann, Marcus Niemann, Hanna Mende, Stefan Störk, Christiane E. Angermann, Jens A. Wagner, Frank Weidemann, Progression of Left Ventricular Functional Abnormalities in Hypertensive Patients with Heart Failure: An Ultrasonic Two-Dimensional Speckle Tracking Study Journal of the American Society of Echocardiography. ,vol. 21, pp. 1309- 1317 ,(2008) , 10.1016/J.ECHO.2008.10.006
Chattanong Yodwut, Roberto M. Lang, Lynn Weinert, Homaa Ahmad, Victor Mor-Avi, Three-dimensional echocardiographic quantitative evaluation of left ventricular diastolic function using analysis of chamber volume and myocardial deformation International Journal of Cardiovascular Imaging. ,vol. 29, pp. 285- 293 ,(2013) , 10.1007/S10554-012-0087-4
A. Thorstensen, H. Dalen, B. H. Amundsen, S. A. Aase, A. Stoylen, Reproducibility in echocardiographic assessment of the left ventricular global and regional function, the HUNT study European Journal of Echocardiography. ,vol. 11, pp. 149- 156 ,(2010) , 10.1093/EJECHOCARD/JEP188
Holly Geyer, Giuseppe Caracciolo, Haruhiko Abe, Susan Wilansky, Scipione Carerj, Federico Gentile, Hans-Joachim Nesser, Bijoy Khandheria, Jagat Narula, Partho P. Sengupta, Assessment of Myocardial Mechanics Using Speckle Tracking Echocardiography: Fundamentals and Clinical Applications Journal of the American Society of Echocardiography. ,vol. 23, pp. 351- 369 ,(2010) , 10.1016/J.ECHO.2010.02.015
Kazuyoshi Doi, Michael W Kopcak Jr, Tomotsugu Tabata, Lisa A Cardon, James D Thomas, Kiyotaka Fukamachi, Masami Takagaki, Patrick M McCarthy, Marlene Goormastic, Yoshie Ochiai, Determinants of the development of mitral regurgitation in pacing-induced heart failure. Circulation. ,vol. 67, pp. 78- 82 ,(2003) , 10.1253/CIRCJ.67.78
Hyungseop Kim, Hong-Won Shin, Jihyun Son, Hyuck-Jun Yoon, Hyoung-Seob Park, Yun-Kyeong Cho, Chun-Duk Han, Chang-Wook Nam, Seung-Ho Hur, Yoon-Nyun Kim, Kwon-Bae Kim, Two-dimensional strain or strain rate findings in mild to moderate diastolic dysfunction with preserved ejection fraction Heart and Vessels. ,vol. 26, pp. 39- 45 ,(2011) , 10.1007/S00380-010-0033-0