Predictors of environmental lead exposure among pregnant women - a prospective cohort study in Poland.

摘要: Blood lead levels (BLL) in women of child-bearing age have been decreasing recent decades, but still remains a concern for long-term effects child psychomotor development. The aim the study was to characterize exposure among Polish pregnant and assess relationship between BLL selected socio-demographic, economic lifestyle factors. population consisted 594 who had subjects prospective Mother Child Cohort Study (REPRO_PL). were interviewed three times during pregnancy (once each trimester. Lead concentration blood collected second trimester analyzed using graphite furnace atomic absorption spectrometry (GF-AAS), or inductively coupled plasma mass (ICP-MS). Active passive smoking by cotinine level saliva liquid chromatography with tandem (LC-MS/MS). ranged from 0.3 - 5.7 μg/dL, geometric mean (GM) 1.1 μg/dL (GSD ±0.2 μg/dL). Statistically significant associations found factors such as maternal (β=0.01; p=0.02), education (β=0.08; p=0.04) prepregnancy BMI (β=0.1; p=0.001). Additionally, increased increasing (β=0.02; p=0.06) decreased distance copper smelter (β=-0.1; p=0.009). Public health interventions, especially regions higher lead, lower SES smokers, are reasonable.