Prognostic significance of the onset mode in parkinsonism

摘要: Early recognition of the prognosis in parkinsonism is important for both management and studies aimed at preventing progression disease. Less favorable reported early-onset postural instability gait difficulty (PIGD) than tremor-onset cases, but reasons this are unknown. In 70 autopsy-verified 11 (15.7%) had PIGD, 34 (49%) tremor onset. Improvement on levodopa was more common tremor-than PIGD-onset cases (p < 0.05). The majority Lewy body disease, while other forms pathology. Survival shorter PIGD-