Efficacy and tolerability of combined topical treatment of acne vulgaris with adapalene and clindamycin: a multicenter, randomized, investigator-blinded study

作者: John E Wolf , David Kaplan , Stephen J Kraus , Keith H Loven , Toivo Rist

DOI: 10.1067/S0190-9622(03)01152-6

关键词:

摘要: … binding profile than tretinoin, acting … Adapalene has greater chemical stability and antiinflammatory effect,14 lower skin irritation potential and significantly better tolerability than …

参考文章(22)
Kligman Am, Mills Oh, Treatment of acne vulgaris with topically applied erythromycin and tretinoin. Acta Dermato-venereologica. ,vol. 58, pp. 555- 557 ,(1978)
Ellis Cn, Gammon Wr, Heezen-Wehner Jl, Stone Dz, A comparison of Cleocin T Solution, Cleocin T Gel, and placebo in the treatment of acne vulgaris. Cutis. ,vol. 42, pp. 245- 247 ,(1988)
Michael H Gold, William J Cunliffe, F William Danby, Alan Greenspan, Frank Dunlap, David Gratton, Randomised, controlled trial of the efficacy and safety of adapalene gel 0.1% and tretinoin cream 0.05% in patients with acne vulgaris European Journal of Dermatology. ,vol. 12, pp. 350- 354 ,(2002)
J. Meynadier, M. Alirezai, Systemic antibiotics for acne. Dermatology. ,vol. 196, pp. 135- 139 ,(1998) , 10.1159/000017847
Galvin, Gilbert, Baker, Guibal, Tuley, Comparative tolerance of adapalene 0.1% gel and six different tretinoin formulations British Journal of Dermatology. ,vol. 139, pp. 34- 40 ,(1998) , 10.1046/J.1365-2133.1998.1390S2034.X
O. H. Mills, Acne vulgaris. Oral therapy with tetracycline and topical therapy with vitamin A Archives of Dermatology. ,vol. 106, pp. 200- 203 ,(1972) , 10.1001/ARCHDERM.106.2.200
MichelL, Jomard, Démarchez, Pharmacology of adapalene British Journal of Dermatology. ,vol. 139, pp. 3- 7 ,(1998) , 10.1046/J.1365-2133.1998.1390S2003.X
Wj Cunliffe, R Caputo, B Dreno, L Förström, M Heenen, Ce Orfanos, Y Privat, A Robledo Aguilar, M Poncet, M Verschoore, Efficacy and safety comparison of adapalene (CD271) gel and tretinoin gel in the topical treatment of acne vulgaris. A European multicentre trial Journal of Dermatological Treatment. ,vol. 8, pp. 173- 178 ,(1997) , 10.3109/09546639709160514