Analysis of ipsilateral breast tumor recurrences after breast-conserving treatment based on the classification of true recurrences and new primary tumors.

摘要: Background Ipsilateral breast tumor recurrences (IBTR) after breast-conserving treatment include two different entities: true recurrence (TR) thought to occur when residual cancer cells grow gradually detectable size and new primary (NP) be de novo independently arising in the preserved breast. The patients with ipsilateral are potentially at high risk for subsequent distant metastasis, but many studies do not distinguish between these types of recurrence. aim this study is clarify biological difference TR NP, show clinical significance classifying IBTR into