Adenosine 3′,5′-cyclic monophosphate derivatives II. Biological activity of some 8-substituted analogs

摘要: Abstract Several 8-substituted derivatives of adenosine 3′,5′-cyclic monophosphate have been shown to stimulate the ATP-dependent phosphorylation histone by purified bovine brain and liver protein kinase as well glycogenolysis in rat slices. The results indicate that a series analogs which varying activation constants (Ka values) for kinases, same order relative potency stimulators