Molecular Epidemiology of HIV-1 Infection among Men who Have Sex with Men in Taiwan in 2012

摘要: The number of men who have sex with (MSM) infected HIV-1 in Taiwan has increased rapidly the past few years. goal this study was to conduct a molecular epidemiological infection among MSM identify risk factors for intervention. Voluntary counseling program and anonymous testing were provided patrons at 1 gay bar, 7 night clubs 3 saunas Taipei New Cities 2012. subtypes determined using gag subtype-specific PCR phylogenetic analysis by env sequences. Recent LAg-Avidity EIA. In-depth interviews questionnaires used factors. prevalence incidence 4.38% (53/1,208) 3.29 per 100 person-years, respectively. Of 49 cases genotyped, 48 (97.9%) subtype B CRF01_AE (2%). Phylogenetic 46 strains showed that 25 (54.4%) formed 9 clusters each other or local strains. case clustered reference strain from Thai blood donor bootstrap value 99. Multivariate logistic regression associated included use oil-based solution as lubricant (vs. saliva water-based lubricants, OR= 4.23; p <0.001); exclusively receptive role insertive role, 9.69; versatile 6.45; p= 0.003); oral 11.93; 0.044); times sexual contact week (2-3 vs. zero week, 3.41; 0.021); illegal drug (OR= 4.12; history sexually transmitted diseases 3.65; 0.002). In conclusion, there no new circulating recombinant form responsible increase Misuse is factor identified Taiwan. Taiwan’s Centers Disease Control created video (www.youtube.com/watch?v=BinExvvOTMM&feature=iv&src_vid=BW81-PfmY3E&annotation_id=annotation_2436493705) correct such misconception its AIDS prevention campaign.