Are there ethnic disparities in risk of preterm birth among infants born with congenital heart defects

摘要: BACKGROUND: Birth defects and preterm birth (PTB) are leading causes of infant morbidity mortality in the United States. Infants with more likely to be born (<37 weeks), yet roles maternal ethnicity fetal growth this relationship unclear. This study aimed assess risk PTB among non-Hispanic (NH) Black, NH-White, Hispanic infants congenital heart (CHD), adjusting for growth. METHODS: Florida Birth Defects Registry data were used conduct a retrospective cohort on 14,319 live-born CHDs January 1, 1998 December 31, 2002. ORs 95% CIs computed each category (small-for-gestational age [SGA], appropriate-for-gestational-age [AGA], large-for-gestational-age [LGA]) by adjusted covariates using logistic regression. RESULTS: After potential confounders, SGA AGA NH-Black had increased compared NH-White (OR 1.79; CI: 1.40, 2.30 OR 1.89; 1.68, 2.13, respectively). SGA, AGA, no infants. CONCLUSIONS: The is not explained overall disparities between NH-Blacks NH-Whites. Additional studies needed determine specific subtypes CHD which these relationships present if findings seen other defects. Research (Part A) 79:754–764, 2007. © 2007 Wiley-Liss, Inc.