作者: Mohamad H. Tiba , Gerard T. Draucker , Brendan M. McCracken , Hasan B. Alam , Jonathan L. Eliason
DOI: 10.1097/TA.0000000000000530
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摘要: BACKGROUND: Hemorrhage is the leading cause of death for both civilian and battlefield injuries. from pelvic vascular wounds concern since it difficult to control before surgical intervention. This has resulted in renewed interest developing presurgical endovascular approaches hemorrhage control. However, likely that other short-term techniques may be needed as a bridge such approaches. We tested prototype device called hemostasis belt (PHB) its ability reduce or halt blood flow lethal model arterial injury. METHODS: Seventeen male swine, 42 (5.2)kg were anesthetized, instrumented, then randomized into three groups (control, military antishock trousers [MAST], PHB). Animals underwent laparotomy with placement 4-0 stainless steel monofilament suture through right iliac artery. The was closed, exteriorized. produced by pulling In PHB MAST groups, devices applied over pelvis lower abdomen 60 minutes, followed release monitoring 30 minutes until animal expired. Hetastarch (500 mL) infused immediately after commencement hemorrhage. RESULTS: All group animals only two survived minutes. Mean (SD) survival time 13 (12.3) Log-rank (Mantel-Cox) analysis demonstrated significant difference when comparing all (p < 0.0001) well = 0.018). Significant differences noted between mean pressure, lactate, central venous hemoglobin oxygen saturation levels. CONCLUSION: successful improving Such helpful methods