C-type natriuretic peptide in vascular physiology and disease
作者： Ramona S. Scotland , Amrita Ahluwalia , Adrian J. Hobbs
DOI: 10.1016/J.PHARMTHERA.2004.08.011
关键词:
摘要: Natriuretic peptides play a critical role in coordination of fluid/electrolyte balance and vascular tone. The renal effects circulating atrial natriuretic peptide (ANP) brain (BNP) are distinct from the paracrine C-type (CNP). CNP is widely expressed throughout vasculature found particularly high concentrations endothelium. Recent studies demonstrate that novel endothelium-derived hyperpolarising factor (EDHF) complements actions other endothelial vasorelaxant mediators such as nitric oxide (NO) prostacyclin. Since several cardiovascular disorders associated with dysfunction activity, selective modulation pathways represents an important therapeutic target; whilst this has been exploited to some degree terms ANP/BNP, potential yet be tapped. This review focuses on recent findings mechanism locally produced endothelial-derived system highlights many avenues for intervention, via CNP-signalling, disease.
unirioja.es
elsevier.com
sci-hub.se 参考文章(72)
T. Yoshimasa, M. Mukoyama, S. Suga, T. Igaki, A. Sugawara, H. Itoh, Y. Komatsu, I. Tanaka, Y. Ogawa, K. Nakao, N. Hama, C-type natriuretic peptide in chronic renal failure and its action in humans. Kidney International. ,vol. 55, ,(1996)
A. L. Clavell, A. J. Stingo, C. M. Wei, D. M. Heublein, J. C. Burnett, C-type natriuretic peptide: a selective cardiovascular peptide American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 264, ,(1993) , 10.1152/AJPREGU.1993.264.2.R290
C. M. Wei, L. L. Aarhus, V. M. Miller, J. C. Burnett, Action of C-type natriuretic peptide in isolated canine arteries and veins. American Journal of Physiology-heart and Circulatory Physiology. ,vol. 264, ,(1993) , 10.1152/AJPHEART.1993.264.1.H71
R. SCOTT WRIGHT, CHI-MING WEI, CHEOL H. KIM, MASAHIKO KINOSHITA, YUZURU MATSUDA, LAWRENCE L. AARHUS, JOHN C. BURNETT, WAYNE L. MILLER, C-type natriuretic peptide-mediated coronary vasodilation: role of the coronary nitric oxide and particulate guanylate cyclase systems. Journal of the American College of Cardiology. ,vol. 28, pp. 1031- 1038 ,(1996) , 10.1016/S0735-1097(96)00241-0
H Schweitz, P Vigne, D Moinier, C Frelin, M Lazdunski, A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis angusticeps). Journal of Biological Chemistry. ,vol. 267, pp. 13928- 13932 ,(1992) , 10.1016/S0021-9258(19)49658-0
Bo Han, Yonathan Hasin, Cardiovascular effects of natriuretic peptides and their interrelation with endothelin-1. Cardiovascular Drugs and Therapy. ,vol. 17, pp. 41- 52 ,(2003) , 10.1023/A:1024255808831
K. Inoue, K. Naruse, S. Yamagami, H. Mitani, N. Suzuki, Y. Takei, Four functionally distinct C-type natriuretic peptides found in fish reveal evolutionary history of the natriuretic peptide system. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 10079- 10084 ,(2003) , 10.1073/PNAS.1632368100
Marek W Radomski, Richard MJ Palmer, Salvador Moncada, None, The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium. Biochemical and Biophysical Research Communications. ,vol. 148, pp. 1482- 1489 ,(1987) , 10.1016/S0006-291X(87)80299-1
A.J. Hobbs, Soluble guanylate cyclase: the forgotten sibling Trends in Pharmacological Sciences. ,vol. 18, pp. 484- 491 ,(1997) , 10.1016/S0165-6147(97)01137-1
A M Vollmar, A L Gerbes, M Nemer, R Schulz, DETECTION OF C-TYPE NATRIURETIC PEPTIDE (CNP) TRANSCRIPT IN THE RAT HEART AND IMMUNE ORGANS Endocrinology. ,vol. 132, pp. 1872- 1874 ,(1993) , 10.1210/ENDO.132.4.8462485