Transfollicular enhancement of methyl myristate loaded in cationic niosomes incorporated in hair lotion.

作者: Jiradej Manosroi , Charinya Chankhampan , Puxvadee Chaikul , Worapaka Manosroi , Aranya Manosroi

DOI: 10.1080/02652048.2016.1228705

关键词:

摘要: Hair lotion containing methyl myristate loaded in cationic niosomes (HL-MMnio) composed of Brij72/cholesterol/DDAB at 7:3:0.65 molar ratio was developed. The remaining percentages MM hair were higher than free about 1.2 times. cumulative amounts porcine skin and the receiver compartment incorporated those 1.45 1.32 times, respectively. HL-MMnio showed very slightly irritation on rabbit skin, which disappeared after 4 d. For melanogenesis induction C57BL/6 mice with aged-induced grey body coat hairs, highest pigmentation scores applied dorsal area observed 21 days, while indicated 35 days. This study has suggested that high potential formulation for canities treatment.

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