Stem Cells in Carcinogenesis of the Prostate
作者： Shi-Ming Tu , Sue-Hwa Lin
DOI: 10.1007/978-1-4471-2864-9_6
关键词:
摘要: A key to solving the beginning of cancer is elucidate its cell origin. Hence, an unspoken appeal stem-cell theory cancers focus on cellular aspects cancer. Many biologic phenomena vital for cells are shared by stem cells. Both and activities tightly regulated their respective microenvironments or niches. Therefore, it not coincidental that epithelial-to-mesenchymal transition (EMT) epithelial-stromal interactions, which critical organogenesis, also play important role in carcinogenesis. We propose a origin encompasses all cancer, including heterogeneity, metastasis, drug resistance, etc., may be our long-sought unified
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