Cancer Drugs, Genetic Variation and the Glutathione- S -Transferase Gene Family

作者: Danyelle M Townsend , Kenneth D Tew

DOI: 10.2165/00129785-200303030-00002

关键词:

摘要: … is altered expression of glutathione-S-transferases (GSTs).[1,2] GSTs are a family of phase II … cellular macromolecules through catalyzing the conjugation of glutathione (GSH) to a wide …

参考文章(144)
G. Philip BOARD, T. Rohan BAKER, Gareth CHELVANAYAGAM, S. Lars JERMIIN, Zeta, a novel class of glutathione transferases in a range of species from plants to humans Biochemical Journal. ,vol. 328, pp. 929- 935 ,(1997) , 10.1042/BJ3280929
Carsten T. Beuckmann, Ko Fujimori, Yoshihiro Urade, Osamu Hayaishi, Identification of mu-class glutathione transferases M2-2 and M3-3 as cytosolic prostaglandin E synthases in the human brain. Neurochemical Research. ,vol. 25, pp. 733- 738 ,(2000) , 10.1023/A:1007579507804
Strange Rc, Fryer Aa, The glutathione S-transferases: influence of polymorphism on cancer susceptibility. IARC scientific publications. pp. 231- ,(1999)
Bengt Mannervik, The Isoenzymes of Glutathione Transferase Advances in Enzymology - and Related Areas of Molecular Biology. ,vol. 57, pp. 357- 417 ,(2006) , 10.1002/9780470123034.CH5
K.E. Comstock, K.J. Johnson, D. Rifenbery, W.D. Henner, Isolation and analysis of the gene and cDNA for a human Mu class glutathione S-transferase, GSTM4. Journal of Biological Chemistry. ,vol. 268, pp. 16958- 16965 ,(1993) , 10.1016/S0021-9258(19)85287-0
Kenneth D. Tew, Glutathione-Associated Enzymes In Anticancer Drug Resistance. Cancer Research. ,vol. 76, pp. 7- 9 ,(2016) , 10.1158/0008-5472.CAN-15-3143
N W Chow, J Whang-Peng, C S Kao-Shan, M F Tam, H C Lai, C P Tu, Human glutathione S-transferases. The Ha multigene family encodes products of different but overlapping substrate specificities. Journal of Biological Chemistry. ,vol. 263, pp. 12797- 12800 ,(1988) , 10.1016/S0021-9258(18)37626-9