A non-lethal malarial infection results in reduced drug metabolizing enzyme expression and drug clearance in mice.

Young-Mi Go, Douglas I Walker, Yongliang Liang, Karan Uppal, Quinlyn A Soltow, ViLinh Tran, Frederick Strobel, Arshed A Quyyumi, Thomas R Ziegler, Kurt D Pennell, Gary W Miller, Dean P Jones, None, Reference Standardization for Mass Spectrometry and High-resolution Metabolomics Applications to Exposome Research Toxicological Sciences. ,vol. 148, pp. 531- 543 ,(2015) , 10.1093/TOXSCI/KFV198

Svensson, Ashton, Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin. British Journal of Clinical Pharmacology. ,vol. 48, pp. 528- 535 ,(1999) , 10.1046/J.1365-2125.1999.00044.X

K M Trotman, J O Peggins, T G Brewer, J M Grace, A J Aguilar, Metabolism of beta-arteether to dihydroqinghaosu by human liver microsomes and recombinant cytochrome P450. Drug Metabolism and Disposition. ,vol. 26, pp. 313- 317 ,(1998)

F. Fontaine, G. de Sousa, P.C. Burcham, P. Duchêne, R. Rahmani, Role of cytochrome P450 3A in the metabolism of mefloquine in human and animal hepatocytes. Life Sciences. ,vol. 66, pp. 2193- 2212 ,(2000) , 10.1016/S0024-3205(00)00546-4

Gilbert Lefèvre, Margaretha Bindschedler, Farkad Ezzet, Nicole Schaeffer, Ingo Meyer, Mikael S Thomsen, Pharmacokinetic interaction trial between co-artemether and mefloquine. European Journal of Pharmaceutical Sciences. ,vol. 10, pp. 141- 151 ,(2000) , 10.1016/S0928-0987(00)00060-9

Gilbert O. Kokwaro, Anthony P. Glazier, Stephen A. Ward, Alasdair M. Breckenridge, Geoffrey Edwards, Effect of malaria infection and endotoxin-induced fever on phenacetin O-deethylation by rat liver microsomes. Biochemical Pharmacology. ,vol. 45, pp. 1235- 1241 ,(1993) , 10.1016/0006-2952(93)90275-2

Shirley Teng, Micheline Piquette-Miller, The Involvement of the Pregnane X Receptor in Hepatic Gene Regulation during Inflammation in Mice Journal of Pharmacology and Experimental Therapeutics. ,vol. 312, pp. 841- 848 ,(2005) , 10.1124/JPET.104.076141

Qianming Bai, Leyuan Xu, Genta Kakiyama, Melissa Ann Runge-Morris, Phillip B. Hylemon, Lianhua Yin, William M. Pandak, Shunlin Ren, Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells. Atherosclerosis. ,vol. 214, pp. 350- 356 ,(2011) , 10.1016/J.ATHEROSCLEROSIS.2010.11.021

Jian Yang, Chunshu Hao, Dongfang Yang, Deshi Shi, Xiulong Song, Xiaofei Luan, Gang Hu, Bingfang Yan, Pregnane X receptor is required for interleukin-6-mediated down-regulation of cytochrome P450 3A4 in human hepatocytes Toxicology Letters. ,vol. 197, pp. 219- 226 ,(2010) , 10.1016/J.TOXLET.2010.06.003

Xue-Qing Li, Anders Bj�rkman, Tommy B. Andersson, Lars L. Gustafsson, Collen M. Masimirembwa, Identification of human cytochrome P(450)s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data. European Journal of Clinical Pharmacology. ,vol. 59, pp. 429- 442 ,(2003) , 10.1007/S00228-003-0636-9