Blood pressure reference intervals for healthy adult chimpanzees (Pan troglodytes)
作者： J.J. Ely , T. Zavaskis , M.L. Lammey , D. Rick Lee
DOI: 10.1111/J.1600-0684.2011.00467.X
关键词:
摘要: Background Cardiovascular disease is the primary cause of morbidity and mortality among captive chimpanzees. But there are no clinical definitions normotension or hypertension in chimpanzees. Methods We analyzed 1 year blood pressure (BP) data from a population 261 healthy adult chimpanzees using consistent set criteria to ascertain health. Results Systolic BP varied by body weight. Diastolic age. Median was 126/63 mmHg, with an upper limit 147/84 mmHg. defined categories pre-hypertension (148/85—153/88 mmHg) (≥154/89 mmHg). The prevalence elevated 15%. relative risk 2.60, compared normotensive animals. Conclusions used contemporary methods human laboratory medicine define reliable reference intervals for chimpanzee BP. Results allow accurate diagnosis pre-hypertension, demonstrate effect on mortality.
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