作者: Ian E. Smith , Mitch Dowsett
DOI: 10.1056/NEJMRA023246
关键词:
摘要: Until recently, tamoxifen, a nonsteroidal antiestrogen, was the mainstay of endocrine treatment breast cancer. However, new aromatase inhibitors that are many times more potent and specific than first such agent, aminoglutethimide, changing management cancer in postmenopausal women. This review discusses role as letrozole, anastrozole, exemestane