Determinants of outcome in patients with sustained ventricular tachyarrhythmias: the antiarrhythmics versus implantable defibrillators (AVID) study registry.

摘要: Abstract Background The prognosis of patients with sustained ventricular tachyarrhythmias varies according to clinical characteristics. We sought identify predictors survival in a large population documented not related reversible or correctable causes included the Antiarrhythmics Versus Implantable Defibrillators (AVID) Registry. Methods and Results analyzed impact 36 demographic, clinical, discharge treatment variables on outcome for 3559 patients. Survival status was assessed use National Death Index. Multivariate analyses were performed Cox proportional hazards model. After mean follow-up 17±12 months, 631 died. Actuarial 0.86 (95% confidence interval [Cl] 0.85 0.88), 0.79 Cl 0.78 0.81), 0.72 0.70 0.74) at 1,2, 3 years. worse older age, severe left dysfunction, lower systolic blood pressure, history congestive heart failure, diabetes, smoking atrial fibrillation, preexistent pacemaker. hemodynamic qualifying arrhythmia predictor outcome. Defibrillator implantation hospital while patient taking β-blocker an angiotensin-converting enzyme inhibitor associated better prognosis. Conclusions Despite therapeutic adbances, mortality rates remain high. Prognosis depends severity underlying disease, as reflected by extent dysfunction presence failure. Well-tolerated tachycardia structural disease does carry significantly than tachyarrhythmia more consequences.