Impact of human immunodeficiency virus infection on the epidemiology, clinical features, management, and control of tuberculosis.

摘要: After years of decreasing prevalence and increasing hope that tuberculosis, like smallpox, could be eliminated, the disease has resurfaced as a major public health problem in United States. Particularly ominous are appearance multiple-drug-resistant strains their impact on patients care workers who infected with human immunodeficiency virus, among whom mortality rates reach 80% 2-3 months postdiagnosis. To respond effectively to this new threat, it is critical we reorient our thinking about tuberculosis redirect resources programs for control. We need reinstitute screening high-risk populations ensure proper isolation disease. Diagnosing at earliest possible stage obviously utmost importance. High priority must given development rapid diagnostic tests techniques screen drug resistance. implement adequately fund drug-discovery develop therapeutic agents effective against Mycobacterium tuberculosis. Effective monitoring treatment also implemented. Failure support such probably led recent upswing especially large cities along eastern seaboard. Leadership funding these come from federal government, specifically U.S. Department Health & Human Services Centers Disease Control (Atlanta). The Infectious Diseases Society America actively supporting variety control-related initiatives will keep its members updated progress area.(ABSTRACT TRUNCATED AT 250 WORDS)