Chapter 27 - Aspects of Future R&D Regarding Targeted Lipid Nanoemulsions

摘要: Self-assembled (colloidal mesophase) lipid nanoemulsions, particularly those predominantly containing dispersed cubic-phase nanoparticles, continue to receive growing research attention. The main reason for this attention is the fact that these nonlamellar nanostructures, such as cubic liquid-crystalline phases, have wide potential delivery systems numerous drugs, cosmetics, and food applications. In a few cases, self-assembled “lipid particle” structure itself (upon injection into bloodstream) demonstrates added advantage of successfully functioning an “active” targeting ligand—which directed via (simple adsorption of) plasma lipoproteins toward appropriate receptors on target-cell surface.