Assessment of radio-protective properties of some anti-inflammatory drugs
作者： M.I. Sayyed , Shams A.M. Issa , Sayed H. Auda
DOI: 10.1016/J.PNUCENE.2017.07.003
关键词:
摘要: Abstract When ionizing radiations are exposed to humans, numerous deleterious health effects including cancer may occur. Recently, radioprotective agents with a novel mode of action have drawn strong interest. Radioprotective able palliate, prevent, or handle radio-induced side-effects. In this study, in the parliamentary procedure investigate some pharmacological compounds, we estimated effective atomic number (Z eff ) and electron density (N e six analgesic anti-inflammatory drugs for total photon interaction energy range 1 keV–100 MeV using WinXCom. addition, by Geometric-Progression (G-P) method, absorption (EABF) exposure buildup factors (EBF) incident 0.015 MeV 15 MeV up penetration depths 40 mean free paths (mfp) were estimated. It has been observed that EABF EBF posses maximum values intermediate region, where Compton scattering is dominant process. Among selected Etodolac (ET) largest EBF, while minimal recorded Meloxicam (ME). The present work could be useful develop compounds used radioprotection, medical diagnostics, radiation therapy.
sci-hub.se 参考文章(31)
Y. Harima, Y. Sakamoto, S. Tanaka, M. Kawai, Validity of the Geometric-Progression Formula in Approximating Gamma-Ray Buildup Factors Nuclear Science and Engineering. ,vol. 94, pp. 24- 35 ,(1986) , 10.13182/NSE86-A17113
Ganesh C Jagetia, None, Radioprotection and radiosensitization by curcumin. Advances in Experimental Medicine and Biology. ,vol. 595, pp. 301- 320 ,(2007) , 10.1007/978-0-387-46401-5_13
Akinao SHIMIZU, Hideo HIRAYAMA, Calculation of Gamma-Ray Buildup Factors up to Depths of 100 mfp by the Method of Invariant Embedding, (II) : Improved Treatment of Bremsstrahlung Journal of Nuclear Science and Technology. ,vol. 40, pp. 192- 200 ,(2003) , 10.1080/18811248.2003.9715349
John L. Wallace, Brian Reuter, Carla Cicala, Webb McKnight, Matthew B. Grisham, Giuseppe Cirino, Novel nonsterodial anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat Gastroenterology. ,vol. 107, pp. 173- 179 ,(1994) , 10.1016/0016-5085(94)90074-4
L. Gerward, S. R. Manohara, S. M. Hanagodimath, Energy absorption buildup factors of human organs and tissues at energies and penetration depths relevant for radiotherapy and diagnostics Journal of Applied Clinical Medical Physics. ,vol. 12, pp. 296- 312 ,(2011) , 10.1120/JACMP.V12I4.3557
Akinao SHIMIZU, Takashi ONDA, Yukio SAKAMOTO, Calculation of Gamma-Ray Buildup Factors up to Depths of 100 mfp by the Method of Invariant Embedding, (III)Generation of an Improved Data Set Journal of Nuclear Science and Technology. ,vol. 41, pp. 413- 424 ,(2004) , 10.1080/18811248.2004.9715503
Tat Khuen Lee, Ieva Stupans, Radioprotection: the non-steroidal anti-inflammatory drugs (NSAIDs) and prostaglandins. Journal of Pharmacy and Pharmacology. ,vol. 54, pp. 1435- 1445 ,(2010) , 10.1211/00223570254
Murat Kurudirek, Sinan Topcuoglu, Investigation of human teeth with respect to the photon interaction, energy absorption and buildup factor Nuclear Instruments & Methods in Physics Research Section B-beam Interactions With Materials and Atoms. ,vol. 269, pp. 1071- 1081 ,(2011) , 10.1016/J.NIMB.2011.03.004
Dariush Sardari, Ali Abbaspour, Samaneh Baradaran, Farshid Babapour, Estimation of gamma- and X-ray photons buildup factor in soft tissue with Monte Carlo method Applied Radiation and Isotopes. ,vol. 67, pp. 1438- 1440 ,(2009) , 10.1016/J.APRADISO.2009.02.033
Joseph Mattana, Saradha Perinbasekar, Claudine Brod-Miller, Near-fatal but reversible acute renal failure after massive ibuprofen ingestion. The American Journal of the Medical Sciences. ,vol. 313, pp. 117- 119 ,(1997) , 10.1016/S0002-9629(15)40068-0