Non-Muscle Invasive Papillary Urothelial Carcinoma Metastatic to the Mandible.

作者: Noah Frydenlund , Yousef Zakharia , Rohan Garje , Laila Dahmoush , Michael A. O’Donnell

DOI: 10.1177/2324709618806332

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摘要: Urothelial carcinoma, the most common histologic subtype of bladder cancer in United States, frequently presents as non-muscle invasive disease. Initially, therapy involves transurethral endoscopic resection and subsequent intravesical therapies with extended surveillance for high-risk Even best treatments, recurrence progression can occur. However, metastasis to distant sites without evidence or regional is rare. In this article, we present case a patient high-grade papillary urothelial carcinoma who developed an unusual mandible, confirmed by GATA-3 immunostaining, over 4 years after initial resection. Prior development metastatic disease, had no local during maintenance Bacillus Calmette-Guerin concurrent surveillance. Positron emission tomography-computed tomography taken presentation mandibular did not show any metastasis. This highlights location occurring muscle disease We additionally highlight utility immunostaining identifying histologically.

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