Effect of ABO blood type on mortality in patients with urothelial carcinoma of the bladder treated with radical cystectomy.

摘要: Objective: ABO blood type is an inherited characteristic that has been associated with the prognosis of several malignancies, but there little evidence in urothelial carcinoma bladder (UCB). The purpose this study was to evaluate effect on mortality patients UCB treated radical cystectomy (RC). Methods: Multi-institutional data from 7,906 RC between 1979 and 2012 were retrospectively analyzed. UCB-related evaluated univariable multivariable competing-risks regression models. Results: O 3,728 (47%), A 2,748 (35%), B 888 (11%), AB 532 (7%) patients. Blood a greater likelihood lymphovascular invasion (P ¼ 0.010) positive soft tissue margins 0.008). median follow-up 41 months. 5-year cumulative rates for O, A, B, 29.5%, 30.5%, 33.2%, 25.8%, respectively. In regression, had worse than those 0.026) 0.020). analysis, however, lost its statistical significance. Conclusions: Among RC, statistically significant clinically insignificant difference mortality. This association not present analysis. Our therefore suggest no relevant