摘要: Recent animal studies have demonstrated evidence of the involvement insulin and insulin-like growth factor (IGF)-I signalling in control ageing longevity. Disruption insulin/IGF-I sig
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A. Bartke, V. Chandrashekar, F. Dominici, D. Turyn, B. Kinney, R. Steger, J.J. Kopchick, Insulin-like growth factor 1 (IGF-1) and aging: controversies and new insights. Biogerontology. ,vol. 4, pp. 1- 8 ,(2003) , 10.1023/A:1022448532248
E. Rinderknecht, R.E. Humbel, The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. Journal of Biological Chemistry. ,vol. 253, pp. 2769- 2776 ,(1978) , 10.1016/S0021-9258(17)40889-1
Holly M. Brown-Borg, Sharlene G. Rakoczy, Mark A. Romanick, Melissa A. Kennedy, Effects of Growth Hormone and Insulin-Like Growth Factor-1 on Hepatocyte Antioxidative Enzymes: Experimental Biology and Medicine. ,vol. 227, pp. 94- 104 ,(2002) , 10.1177/153537020222700203
Andrea M Vincent, Eva L Feldman, Control of cell survival by IGF signaling pathways. Growth Hormone & Igf Research. ,vol. 12, pp. 193- 197 ,(2002) , 10.1016/S1096-6374(02)00017-5
Paulo F. Collett-Solberg, Pinchas Cohen, Genetics, chemistry, and function of the IGF/IGFBP system. Endocrine. ,vol. 12, pp. 121- 136 ,(2000) , 10.1385/ENDO:12:2:121
Giuseppe Paolisso, Stefania Ammendola, Andrea Del Buono, Antonio Gambardella, Mariangela Riondino, Maria Rosaria Tagliamonte, Maria Rosaria Rizzo, Carlo Carella, Michele Varricchio, Serum Levels of Insulin-Like Growth Factor-I (IGF-I) and IGF-Binding Protein-3 in Healthy Centenarians: Relationship with Plasma Leptin and Lipid Concentrations, Insulin Action, and Cognitive Function The Journal of Clinical Endocrinology and Metabolism. ,vol. 82, pp. 2204- 2209 ,(1997) , 10.1210/JCEM.82.7.4087
Martin Holzenberger, Joëlle Dupont, Bertrand Ducos, Patricia Leneuve, Alain Géloën, Patrick C. Even, Pascale Cervera, Yves Le Bouc, IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice Nature. ,vol. 421, pp. 182- 187 ,(2003) , 10.1038/NATURE01298
Holly M. Brown-Borg, Hormonal regulation of aging and life span Trends in Endocrinology & Metabolism. ,vol. 14, pp. 151- 153 ,(2003) , 10.1016/S1043-2760(03)00051-1
K Brismar, E Fernqvist-Forbes, J Wahren, K Hall, Effect of insulin on the hepatic production of insulin-like growth factor-binding protein-1 (IGFBP-1), IGFBP-3, and IGF-I in insulin-dependent diabetes The Journal of Clinical Endocrinology and Metabolism. ,vol. 79, pp. 872- 878 ,(1994) , 10.1210/JCEM.79.3.7521354
Panagiotis Kokkoris, F.Xavier Pi-Sunyer, Obesity and endocrine disease Endocrinology and Metabolism Clinics of North America. ,vol. 32, pp. 895- 914 ,(2003) , 10.1016/S0889-8529(03)00078-1