Myocardial aging: functional alterations and related cellular mechanisms

摘要: Studies that have examined the effect of age on myocardium do not support notion a generalized decline in myocardial function occurs with adult aging but, rather, certain specific changes cardiac biochemistry and occur. Although many instances molecular bases for these been precisely defined, sufficient clues regarding their nature are at hand to provide least first step toward an understanding dramatic effects or time myocardium. A fundamental will additional dimension studies may be useful elucidating mechanisms excitation-contraction coupling heart.