Evaluation Of The Gen-Probe Amplified Mycobacterium Tuberculosis Direct Test For The Routine Diagnosis Of Pulmonary Tuberculosis
作者： Françoise Portaels , E Serruys , H De Beenhouwe , Josiane Degraux , K De Ridde
DOI: 10.1080/17843286.1996.11718502
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摘要: SummaryA total of 624 respiratory specimens from 543 patients (418 Belgian, 110 Rwandan, and 15 Colombian patients) were tested for the presence Mycobacterium tuberculosis by Tuberculosis Direct Test (MTDT, Gen-Probe). Compared to culture, MTDT on 497 samples sputum or broncho-alveolar lavage Belgium had a sensitivity, specificity positive negative predictive value 86.4%, 96.0%, 50.0% 99.3% respectively. The pooled results Rwanda (112 specimens) Colombia (15 97.8%, 65.7%, 88.2%, 92% After resolution discrepant taking into account clinical data, Belgian 86.9%, 96.2%, 52.6%, respectively, Rwandan-Colombian 98.1%, 100%, 100% respectively.Results could be improved testing more than one specimen each patient inclusion an internal control detect inhibitors reaction. Culture remains necessary drug susceptibili...
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