Phase Ib study of dovitinib in combination with gemcitabine plus cisplatin or gemcitabine plus carboplatin in patients with advanced solid tumors

作者: Matthew D. Galsky , Marshall Posner , Randall F. Holcombe , Karen M. Lee , Krzysztof Misiukiewicz

DOI: 10.1007/S00280-014-2518-5

关键词:

摘要: Purpose Dovitinib is a small molecule kinase inhibitor with activity against the fibroblast growth factor and vascular endothelial receptor families. The purpose of this phase Ib study was to define recommended 2 dose combinations gemcitabine cisplatin or carboplatin plus dovitinib.

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