Multi plasmid system for the production of influenza virus
作者： Hong Jin , Erich Hoffman , Greg Duke , Bin Lu , George William Kemble
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摘要: Vectors and methods for the production of influenza viruses suitable as recombinant vaccines in cell culture are provided. Bi-directional expression vectors use a multi-plasmid virus system Additionally, invention provides producing with enhanced ability to replicate embryonated chicken eggs and/or cells (e.g., Vero MDCK) further replication characteristics. In addition, present includes an improved method rescue, wherein animal SF cells) electroporated plasmids invention.
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