Laparoscopic resection for hepatocellular carcinoma: a matched-pair comparative study

摘要: Only a few series have demonstrated the safety of laparoscopic resection for hepatocellular carcinoma (HCC) and benefits this approach. Moreover, these studies reported mostly minor nonanatomic hepatic resections. This report describes results pair-matched comparative study between open liver resections HCC in essentially anatomic Patients were retrospectively matched pairs following criteria: sex, age, American Society Anesthesiology (ASA) score, severity disease, tumor size, type resection. A total 42 patients undergoing laparoscopy compared with laparotomy during same period. Surgeons from authors’ department not trained performed Operative, postoperative, oncologic outcomes compared. The mean duration surgery was similar two groups. Significantly less bleeding observed group (364.3 vs. 723.7 ml; p < 0.0001). Transfusion required four (9.5%) seven (16.7%) (p = 0.51). Postoperative ascites frequent after (7.1 26.1%; p = 0.03). General morbidity groups (9.5 11.9%; p = 1.00). hospital stay significantly shorter (6.7 9.6 days; surgical margin local recurrence adjacent to stump affected by laparoscopy. overall postoperative survival rates 93.1% at 1 year, 74.4% 3 years, 59.5% 5 years and, respectively, 81.8, 73, 47.4% (p = 0.25). disease-free 81.6% 60.9% 45.6% 5 years, 70.2, 54.3, 37.2% (p = 0.29). Laparoscopic selected gave better outcome without consequences. Prospective trials are confirm results.