Studies on permeability in relation to nerve function. III. Permittivity of brain cortex slices to glycin and aspartic acid.
作者： Saul R. Korey , R. Mitchell
DOI: 10.1016/0006-3002(51)90065-0
关键词:
摘要: Cortical tissue slices of rabbit were exposed to 15N labeled glycine, aspartic acid, and urea. The rates penetration these substances into the interstitial compartment neuronal cells determined. Factors, such as temperature, respiratory inhibition, acetylcholinesterase inactivation studied with regard their effect on permeability amino acids. The following results obtined: 1. 1. capacity space determined by inulin method was found vary between 19 34% average 30% total volume. 2. 2. Q10 passage glycine close 1.o; in contrast 4, that asparatic acid about 2.4. 3. 3. Respiratory inhibition cyanide diminished rate entry cells; to, unaffected. 4. 4. Inhibitors did not exert a significant cellular acids.
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