Multinutrient Approach to Slow Down Brain Aging and Related Neurodegenerative Disorders

摘要: Abstract Old age is the greatest risk factor for most of neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and stroke, all marked by global deficits in cognitive abilities impaired neuronal function. The pharmacological interventions age-related disorders are limited not yet rewarding, also associated with significant adverse effects. Multinutrients including micronutrients, macronutrients (protein amino acids, fats, carbohydrates, vitamins, omega-3 polyunsaturated fatty acids), other nutrients secondary plant metabolites may prolong onset dementia slow down brain aging. Recent findings suggest that dietary supplementation caloric restriction mimetics vegetable or fruit extracts exerts their beneficial effects decreasing age-dependent vulnerability toward oxidative stress neurodegeneration. present chapter provides an extensive overview on potential multinutrients to prevent events improve function during