Monitoring of metal and metalloid content in dietary supplements on the Croatian market

作者: H. Tumir , J. Bošnir , I. Vedrina-Dragojević , Z. Dragun , S. Tomić

DOI: 10.1016/J.FOODCONT.2009.12.005

关键词:

摘要: Thirty samples of widely used vitamins and herbal preparations distributed on the Croatian market were analysed by atomic absorption spectrometry in order to estimate contamination with Pb, Cd, As, Hg, Cr, Ni Zn due their potential toxicity if present above maximum allowable levels (MAL). The following concentration ranges obtained (in g g-1): Pb 0.25-3.86 ; Cd 0.05-0.28 As 0.10-0.19 Hg 0.02-0.12 Cr 0.11-64.38 0.24-338.90 1.00-95.3. Several formulations had metal limits (Pb: one honey-based product medicinal herb-based Cr: containing Ni: two products animal origin). Moreover, estimated cumulative daily intakes several metals from some dietary supplements higher than oral permitted exposures set USP Advisory Panel impurities minerals Such a significant additional source human diet, therefore could be harmful for health.

参考文章(17)
Maja Blanuša, Antun Kučak, Validation of microwave digestion method for determination of trace metals in mushrooms. Arhiv Za Higijenu Rada I Toksikologiju. ,vol. 49, pp. 335- 342 ,(1998)
Phillip L. Williams, Stephen M. Roberts, Robert C. James, Principles of Toxicology: Environmental and Industrial Applications ,(2015)
Ikhlas A Khan, James Allgood, Larry A Walker, Ehab A Abourashed, Daniel Schlenk, William H Benson, Determination of heavy metals and pesticides in ginseng products. Journal of AOAC International. ,vol. 84, pp. 936- 939 ,(2001) , 10.1093/JAOAC/84.3.936
Steven G. Donkin, Danny L. Ohlson, Christopher M. Teaf, Properties and Effects of Metals John Wiley & Sons, Ltd. pp. 325- 344 ,(2003) , 10.1002/0471231800.CH14
Gunnar Nordberg, Excursions of intake above ADI: case study on cadmium. Regulatory Toxicology and Pharmacology. ,vol. 30, ,(1999) , 10.1006/RTPH.1999.1327
N. S. Rajurkar, M. M. Damame, Elemental analysis of some herbal plants used in the treatment of cardiovascular diseases by NAA and AAS Journal of Radioanalytical and Nuclear Chemistry. ,vol. 219, pp. 77- 80 ,(1997) , 10.1007/BF02040269
E.D. Caldas, L.L. Machado, Cadmium, mercury and lead in medicinal herbs in Brazil. Food and Chemical Toxicology. ,vol. 42, pp. 599- 603 ,(2004) , 10.1016/J.FCT.2003.11.004
Edzard Ernst, Harmless herbs? A review of the recent literature. The American Journal of Medicine. ,vol. 104, pp. 170- 178 ,(1998) , 10.1016/S0002-9343(97)00397-5
Scott P. Dolan, David A. Nortrup, P. Michael Bolger, Stephen G. Capar, Analysis of dietary supplements for arsenic, cadmium, mercury, and lead using inductively coupled plasma mass spectrometry. Journal of Agricultural and Food Chemistry. ,vol. 51, pp. 1307- 1312 ,(2003) , 10.1021/JF026055X
Gregory J. Garvey, Gary Hahn, Richard V. Lee, Raymond D. Harbison, Heavy metal hazards of Asian traditional remedies. International Journal of Environmental Health Research. ,vol. 11, pp. 63- 71 ,(2001) , 10.1080/09603120020019656