Genome shuffling of Lactobacillus for improved acid tolerance.

作者: Ranjan Patnaik , Susan Louie , Vesna Gavrilovic , Kim Perry , Willem P.C. Stemmer

DOI: 10.1038/NBT0702-707

关键词:

摘要: Fermentation-based bioprocesses rely extensively on strain improvement for commercialization. Whole-cell biocatalysts are commonly limited by low tolerance of extreme process …

参考文章(42)
J. McLaren, The technology roadmap for plant/crop-based renewable resources 2020 Other Information: PBD: 22 Feb 1999. ,(1999)
C. S. Gong, N. J. Cao, J. Du, G. T. Tsao, Ethanol Production from Renewable Resources Recent Progress in Bioconversion of Lignocellulosics. ,vol. 65, pp. 207- 241 ,(1999) , 10.1007/3-540-49194-5_9
Sang Yup Lee, Jong-il Choi, Production of Microbial Polyester by Fermentation of Recombinant Microorganisms Advances in Biochemical Engineering \/ Biotechnology. ,vol. 71, pp. 183- 207 ,(2001) , 10.1007/3-540-40021-4_6
Fabien Rallu, Alexandra Gruss, S. Dusko Ehrlich, Emmanuelle Maguin, Acid- and multistress-resistant mutants of Lactococcus lactis : identification of intracellular stress signals. Molecular Microbiology. ,vol. 35, pp. 517- 528 ,(2002) , 10.1046/J.1365-2958.2000.01711.X
Jeffrey J. Kolstad, Aharon M. Eyal, Betty Hazan, Avraham M. Baniel, Brenda F. Stewart, Joseph Mizrahi, Rod R. Fisher, Process for isolating lactic acid ,(1998)
Jeffrey H Miller, Experiments in molecular genetics ,(1972)
Jon Eness, Stephen B. Del Cardayré, Jeremy Minshull, Willem P.C. Stemmer, Molecular breeding: The natural approach to protein design Advances in Protein Chemistry. ,vol. 55, pp. 261- 292 ,(2001) , 10.1016/S0065-3233(01)55006-8
Nay-Wei Soong, Laurel Nomura, Katja Pekrun, Margaret Reed, Liana Sheppard, Glenn Dawes, Willem P.C. Stemmer, Molecular breeding of viruses. Nature Genetics. ,vol. 25, pp. 436- 439 ,(2000) , 10.1038/78132
Andreas Crameri, Sun-Ai Raillard, Ericka Bermudez, Willem P. C. Stemmer, DNA shuffling of a family of genes from diverse species accelerates directed evolution Nature. ,vol. 391, pp. 288- 291 ,(1998) , 10.1038/34663
Claudia Schmidt-Dannert, Daisuke Umeno, Frances H. Arnold, Molecular breeding of carotenoid biosynthetic pathways Nature Biotechnology. ,vol. 18, pp. 750- 753 ,(2000) , 10.1038/77319