Control of saccadic eye movements and combined eye/head gaze shifts by the medio-posterior cerebellum.

作者: Denis Pélisson , Laurent Goffart , Alain Guillaume

DOI: 10.1016/S0079-6123(03)42007-4

关键词:

摘要: The cerebellar areas involved in the control of saccades have recently been identified medio-posterior cerebellum (MPC). Unit activity recordings, experimental lesions and electrical microstimulation this region cats monkeys provided a considerable amount data allowed development new computational models. In paper, we review these concepts about function, discuss their importance limitations suggest future directions for research. anatomical indicate that MPC has more than one site action visuo-oculomotor system. contrast, most models emphasize role connections with immediate pre-oculomotor circuits reticular formation, only recent model also incorporates ascending projections to superior colliculus. A major challenge studies, continuation initial attempt, is determine whether various output pathways correspond distinct contributions saccadic eye movements. Also, series studies cat indicated general orienting movements space, calling an increasing effort study production head-unrestrained gaze shifts.

参考文章(176)
W. F. Crandall, E. L. Keller, Visual and oculomotor signals in nucleus reticularis tegmenti pontis in alert monkey. Journal of Neurophysiology. ,vol. 54, pp. 1326- 1345 ,(1985) , 10.1152/JN.1985.54.5.1326
A. F. Fuchs, F. R. Robinson, A. Straube, Role of the caudal fastigial nucleus in saccade generation. I. Neuronal discharge pattern. Journal of Neurophysiology. ,vol. 70, pp. 1723- 1740 ,(1993) , 10.1152/JN.1993.70.5.1723
Laurent Goffart, Denis Pélisson, Orienting Gaze Shifts During Muscimol Inactivation of Caudal Fastigial Nucleus in the Cat. I. Gaze Dysmetria Journal of Neurophysiology. ,vol. 79, pp. 1942- 1958 ,(1998) , 10.1152/JN.1998.79.4.1942
F. R. Robinson, A. Straube, A. F. Fuchs, Role of the caudal fastigial nucleus in saccade generation. II. Effects of muscimol inactivation Journal of Neurophysiology. ,vol. 70, pp. 1741- 1758 ,(1993) , 10.1152/JN.1993.70.5.1741
Robert H. Wurtz, Michael E. Goldberg, The Neurobiology of Saccadic Eye Movements ,(1989)
George E. Stelmach, Jean Requin, Tutorials in motor behavior North-Holland , Sole distributors for the U.S.A. and Canada, Elsevier North-Holland. ,(1980)
The Cerebellum—New Vistas Springer Berlin Heidelberg. ,(1982) , 10.1007/978-3-642-68560-6