Antibody-Maytansinoid Conjugates Are Activated in Targeted Cancer Cells by Lysosomal Degradation and Linker-Dependent Intracellular Processing
作者： Hans K. Erickson , Peter U. Park , Wayne C. Widdison , Yelena V. Kovtun , Lisa M. Garrett
DOI: 10.1158/0008-5472.CAN-05-4489
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摘要: … 2A display signals for the amount of radioactivity in the acetone-… were isolated and found by mass spectrometry (MS) to be the … factors (for a review, see ref. 22), direct cytotoxicity of all …
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