Bovine viral diarrhea virus proteins and their antigenic analyses.
作者： R. O. Donis , W. V. Corapi , E. J. Dubovi
DOI: 10.1007/978-3-7091-9153-8_4
关键词:
摘要: Bovine Viral Diarrhea Virus (BVDV) polypeptides present in infected cells are the result of processing polyprotein translated from large single open reading frame BVDV genomic RNA. The presence these proteins was studied by radiolabeling under hypertonic conditions and with aid radioimmunoprecipitation. mapping suggests a complex pattern which involves cellular viral proteases. consistent absence 80k noncytopathic isolates that is different cytopathic biotypes BVDV. antigenic structure panel monoclonal antibodies (MABs) prepared against Singer isolate Neutralizing MABs were found to bind 56-58k polypeptide, providing evidence this glycoprotein on surface virion carries neutralization epitopes. Antigenic analyses reveals extensive heterogeneity among field isolates. used determine frequency escape mutants stocks Plaque-purified contain 10(-2.47).
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sci-hub.st 参考文章(41)
Baker Jc, Bovine viral diarrhea virus: a review. Javma-journal of The American Veterinary Medical Association. ,vol. 190, pp. 1449- 1458 ,(1987)
W. R. Pritchard, A. J. Kniazeff, Antigenic relationships in the bovine viral diarrhea-mucosal disease complex. Antigenic relationships in the bovine viral diarrhea-mucosal disease complex.. ,(1961)
Steven W. Kessler, Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A. Journal of Immunology. ,vol. 115, pp. 1617- 1624 ,(1975)
W V Corapi, R O Donis, E J Dubovi, Monoclonal antibody analyses of cytopathic and noncytopathic viruses from fatal bovine viral diarrhea virus infections. Journal of Virology. ,vol. 62, pp. 2823- 2827 ,(1988) , 10.1128/JVI.62.8.2823-2827.1988
G R Larsen, E Wimmer, E A Emini, B A Jameson, A J Lewis, Poliovirus neutralization epitopes: analysis and localization with neutralizing monoclonal antibodies. Journal of Virology. ,vol. 43, pp. 997- 1005 ,(1982) , 10.1128/JVI.43.3.997-1005.1982
R Crainic, P Couillin, B Blondel, N Cabau, A Boué, F Horodniceanu, Natural variation of poliovirus neutralization epitopes. Infection and Immunity. ,vol. 41, pp. 1217- 1225 ,(1983) , 10.1128/IAI.41.3.1217-1225.1983
Hooshmand Sheshberadaran, Erling Norrby, Characterization of epitopes on the measles virus hemagglutinin Virology. ,vol. 152, pp. 58- 65 ,(1986) , 10.1016/0042-6822(86)90371-5
Michael J. Birrer, Stephen Udem, Stanley Nathenson, Barry R. Bloom, Antigenic variants of measles virus. Nature. ,vol. 293, pp. 67- 69 ,(1981) , 10.1038/293067A0
R. O. Donis, E. J. Dubovi, Characterization of bovine viral diarrhoea-mucosal disease virus-specific proteins in bovine cells. Journal of General Virology. ,vol. 68, pp. 1597- 1605 ,(1987) , 10.1099/0022-1317-68-6-1597
Marc S. Collett, Ruby Larson, Susan K. Belzer, Ernest Retzel, Proteins encoded by bovine viral diarrhea virus: the genomic organization of a pestivirus. Virology. ,vol. 165, pp. 200- 208 ,(1988) , 10.1016/0042-6822(88)90673-3