An Efficient Synthesis of 3‐OBn‐6β,14‐Epoxy‐Bridged Opiates from Naltrexone and Identification of a Related Dual MOR Inverse Agonist/KR Agonist.
作者： David J. Martin , Paul E. FitzMorris , Bo Li , Mario Ayestas , Ellicott J. Sally
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David J. Martin, Paul E. FitzMorris, Bo Li, Mario Ayestas, Ellicott J. Sally, Christina M. Dersch, Richard B. Rothman, Amy M. Deveau, An efficient synthesis of 3-OBn-6β,14-epoxy-bridged opiates from naltrexone and identification of a related dual MOR inverse agonist/KOR agonist. Bioorganic & Medicinal Chemistry Letters. ,vol. 22, pp. 6801- 6805 ,(2012) , 10.1016/J.BMCL.2012.06.056