作者: Jamil Akkad , Sylvia Bochum , Uwe M. Martens
DOI: 10.1007/S00423-015-1276-0
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摘要: Background Colorectal cancer (CRC) is the third most common diagnosed worldwide and continues to be a major healthcare concern. Molecular heterogeneity of CRC believed one main factors responsible for considerable variability in treatment response. With recent development powerful genomic technologies, novel insights tumor biology have now been provided, facilitating recognition new molecular subtypes with prognostic predictive implications.