Whole genome re-sequencing reveals recent signatures of selection in three strains of farmed Nile tilapia ( Oreochromis niloticus )

摘要: Nile tilapia belongs to the second most cultivated group of fish in world, mainly because its favorable characteristics for production. Genetic improvement programs and domestication process may have modified genome through selective pressure, leaving signals that can be detected at molecular level. In this work, signatures selection were identified using genome-wide SNP data, by two haplotype-based (iHS Rsb) one FST based method. Whole-genome re-sequencing 326 individuals from three strains (A, B C) farmed maintained Brazil Costa Rica was carried out Illumina HiSeq 2500 technology. After applying conventional SNP-calling quality-control filters, ~ 1.3 M high-quality SNPs inferred used as input iHS, Rsb methods. We several candidate genes putatively subjected each strain. A considerable number these are associated with growth (e.g. NCAPG, KLF3, TBC1D1, TTN), early development FGFR3, PFKFB3), immunity traits NLRC3, PIGR, MAP1S). These represent putative genomic landmarks could biological commercial interest tilapia.