Developmental model of static allometry in holometabolous insects

摘要: The regulation of static allometry is a fundamental developmental process, yet little understood the mechanisms that ensure organs scale correctly across range body sizes. Recent studies have revealed physiological and genetic control nutritional variation in final organ size holometabolous insects. implications these for is, however, unknown. Here, we formulate mathematical description Drosophila melanogaster use it to explore how regulators influence allometry. model suggests slope allometries, ‘allometric coefficient’, controlled by relative sensitivity an organ's growth rate changes nutrition, duration development when nutrition affects size. also predicts that, order maintain correct scaling, varies among organs, within through time. We present experimental data support predictions. By revealing specific allometry, serves identify processes upon which evolution may act alter scaling relationships.