Mathematical modeling of the female reproductive system: from oocyte to delivery

作者: Alys R Clark , Jennifer A Kruger

DOI: 10.1002/WSBM.1353

关键词:

摘要: From ovulation to delivery, and through the menstrual cycle, female reproductive system undergoes many dynamic changes provide an optimal environment for embryo implant, develop successfully. It is difficult ethically practically observe over timescales involved in growth development (often hours days). Even carefully monitored conditions clinicians biologists can only see snapshots of process. Mathematical models are emerging as a key means supplement our knowledge process, tease apart complexity system. These have been used successfully test existing hypotheses regarding mechanisms infertility pathological fetal development, also new experimentally testable process development. This has allowed improvements assisted technologies moving toward translation clinical practice via multiscale assessments dynamics ovulation, pregnancy, timing mechanics delivery. WIREs Syst Biol Med 2017, 9:e1353. doi: 10.1002/wsbm.1353 For further resources related this article, please visit website.

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