作者: Roman Elashnikov , Oleksiy Lyutakov , Pavel Ulbrich , Vaclav Svorcik
DOI: 10.1016/J.MSEC.2016.03.047
关键词:
摘要: The creation of an antibacterial material with triggerable properties enables us to avoid the overuse or misuse substances and, thus, prevent emergence resistant bacterial strains. As a potential light-activated material, polymethylmethacrylate (PMMA) nanofibers doped silver nanoparticles (AgNPs) and meso-tetraphenylporphyrin (TPP) were prepared by electrospinning. TPP was chosen as effectively reactive oxygen species (ROS) producer. Antibacterial tests on Staphylococcus epidermidis (S. epidermidis) Enterococcus faecalis (E. faecalis) showed excellent light-triggerable activity materials. Upon light irradiation at wavelength corresponding absorption peak (405nm), dramatically increased, mostly due release AgNPs from polymer matrix. Furthermore, under prolonged irradiation, AgNPs/TPP/PMMA nanofibers, displayed enhanced longevity photothermal stability. Thus, our results suggest that proposed is promising option for photodynamic inactivation bacteria.