Light-activated polymethylmethacrylate nanofibers with antibacterial activity

作者: Roman Elashnikov , Oleksiy Lyutakov , Pavel Ulbrich , Vaclav Svorcik

DOI: 10.1016/J.MSEC.2016.03.047

关键词:

摘要: The creation of an antibacterial material with triggerable properties enables us to avoid the overuse or misuse substances and, thus, prevent emergence resistant bacterial strains. As a potential light-activated material, polymethylmethacrylate (PMMA) nanofibers doped silver nanoparticles (AgNPs) and meso-tetraphenylporphyrin (TPP) were prepared by electrospinning. TPP was chosen as effectively reactive oxygen species (ROS) producer. Antibacterial tests on Staphylococcus epidermidis (S. epidermidis) Enterococcus faecalis (E. faecalis) showed excellent light-triggerable activity materials. Upon light irradiation at wavelength corresponding absorption peak (405nm), dramatically increased, mostly due release AgNPs from polymer matrix. Furthermore, under prolonged irradiation, AgNPs/TPP/PMMA nanofibers, displayed enhanced longevity photothermal stability. Thus, our results suggest that proposed is promising option for photodynamic inactivation bacteria.

参考文章(44)
R. Elashnikov, O. Lyutakov, Y. Kalachyova, A. Solovyev, V. Svorcik, Tunable release of silver nanoparticles from temperature-responsive polymer blends Reactive & Functional Polymers. ,vol. 93, pp. 163- 169 ,(2015) , 10.1016/J.REACTFUNCTPOLYM.2015.06.010
Mahdi Adabi, Reza Saber, Majid Naghibzadeh, Farnoush Faridbod, Reza Faridi-Majidi, Parameters affecting carbon nanofiber electrodes for measurement of cathodic current in electrochemical sensors: an investigation using artificial neural network RSC Advances. ,vol. 5, pp. 81243- 81252 ,(2015) , 10.1039/C5RA15541J
Jiří Mosinger, Oldřich Jirsák, Pavel Kubát, Kamil Lang, Bedřich Mosinger, Bactericidal nanofabrics based on photoproduction of singlet oxygen Journal of Materials Chemistry. ,vol. 17, pp. 164- 166 ,(2007) , 10.1039/B614617A
Zhisong Lu, Chang Ming Li, Haifeng Bao, Yan Qiao, Yinghui Toh, Xu Yang, Mechanism of antimicrobial activity of CdTe quantum dots. Langmuir. ,vol. 24, pp. 5445- 5452 ,(2008) , 10.1021/LA704075R
Soňa Jesenská, Lukáš Plíštil, Pavel Kubát, Kamil Lang, Libuše Brožová, Štěpán Popelka, Lórant Szatmáry, Jiří Mosinger, Antibacterial nanofiber materials activated by light Journal of Biomedical Materials Research Part A. ,vol. 99, pp. 676- 683 ,(2011) , 10.1002/JBM.A.33218
P. Slepička, R. Elashnikov, P. Ulbrich, M. Staszek, Z. Kolská, V. Švorčík, Stabilization of sputtered gold and silver nanoparticles in PEG colloid solutions Journal of Nanoparticle Research. ,vol. 17, pp. 1- 15 ,(2015) , 10.1007/S11051-014-2850-Z
L. Brovko, H. Anany, M. Bayoumi, K. Giang, E. Kunkel, E. Lim, O. Naboka, S. Rahman, J. Li, C.D.M. Filipe, M.W. Griffiths, Antimicrobial light‐activated materials: towards application for food and environmental safety Journal of Applied Microbiology. ,vol. 117, pp. 1260- 1266 ,(2014) , 10.1111/JAM.12622
Sacha Noimark, Jonathan Weiner, Nuruzzaman Noor, Elaine Allan, Charlotte K. Williams, Milo S. P. Shaffer, Ivan P. Parkin, Dual‐Mechanism Antimicrobial Polymer–ZnO Nanoparticle and Crystal Violet‐Encapsulated Silicone Advanced Functional Materials. ,vol. 25, pp. 1367- 1373 ,(2015) , 10.1002/ADFM.201402980
O. Lyutakov, Y. Kalachyova, A. Solovyev, S. Vytykacova, J. Svanda, J. Siegel, P. Ulbrich, V. Svorcik, One-step preparation of antimicrobial silver nanoparticles in polymer matrix Journal of Nanoparticle Research. ,vol. 17, pp. 120- ,(2015) , 10.1007/S11051-015-2935-3
Kevin G. Stamplecoskie, Juan C. Scaiano, Light emitting diode irradiation can control the morphology and optical properties of silver nanoparticles. Journal of the American Chemical Society. ,vol. 132, pp. 1825- 1827 ,(2010) , 10.1021/JA910010B