Chapter 8 Lipophilic and polar indices

摘要: Publisher Summary The model of interaction indices considers the interactions in mobile phase as driving force retention and understands separation result differences polarities molecules characterized by size molecules, that is, their molar volumes. However, a single index is insufficient to take into account different selectivity effects. Different polarity should be used for phases containing solvents belonging classes according Snyder's classification. relative polar directly proportional difference between solute with functional group its unsubstituted parent compound, and, therefore, it can expected increase groups molecule solute. As reflect selective solutes specific phase, values various organic solvents.