Implanted cardiovascular polymers: Natural, synthetic and bio-inspired

摘要: Abstract This review details the use of polymeric biomaterials used in implantable cardiovascular devices. Specifically, role polymer two major types device, vascular graft and stent, is examined critically. In these devices, device performance critically dependent on polymer; material requirements are detailed, shortcomings currently polymers highlighted with a view to furthering development new materials. each category, synthetic polymers, natural origin, that mimic proteins but synthesized, have all been evaluated varying degrees success. We find totally artificial still preferred option when autologous vessels not available; completely tissue-engineered awaits improvements scaffold materials as well tissue reactor engineering. field stents, current consensus driving substitution biodegradable, stent for biostable metallic one. Although various biodegradable evaluated, hydrolytically degradable polyesters continue be choice. New developments highlighted, their terms biocompatibility controlled degradability presented. The outlook next decade appears hopeful, cell-seeding cell growth techniques expected enhance both implanted device.