Monitoring Cerebral Oxygenation: Experimental Studies and Preliminary Clinical Results of Continuous Monitoring of Cerebrospinal Fluid and Brain Tissue Oxygen Tension

作者: A. I. R. Maas , W. Fleckenstein , D. A. Jong , H. Santbrink

DOI: 10.1007/978-3-7091-9302-0_9

关键词:

摘要: Cerebral ischaemia is considered to be the central mechanism leading secondary brain damage in patients with severe head injury. It would therefore seem appropriate monitor cerebral oxygenation these patients. The possibilities of continuous monitoring tissue and CSF oxygen tension as parameters for were evaluated. In experimental studies influence changed offer decreased perfusion pressure on pO2 investigated. Fast changes observed response decreasing offer. Slower noted hypo- hyperventilation. An autoregulatory regulating postulated. Reducing both pO2, but reperfusion phase after complete a dissociation occurred between being restored, remaining low or even further. From it concluded that reflect caused by well blood flow. Brain also sensitive demand from tissue.

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