The Human Teratomas: Experimental And Clinical Biology

摘要: 1 History of Teratomas.- Early Morphologic and Clinical Studies Ovarian Theories the Origin Testicular Extragonadal Teratomas in Animals.- Experimental Studies.- References.- 2 The Pathology Human Classification Germ Cell Tumors.- Histopathology.- Embryonal Carcinoma.- Somatic Tissues.- Extraembryonic Nonneoplastic Components Variant Forms Related Lesions.- Monophyletic or Unilaterally Differentiated Mixed Teratoid Mullerian Fetus Fetu.- Site Sacrococcygeal Retroperitoneal Mediastinal Neck.- Intracranial Unusual Locations.- Associated Lesions Abnormalities.- Twinning.- Association Malformations.- Chromosomal Abnormalities Genetic Predisposition to Disturbances Immune System.- 3 Dermoid Cyst (Benign Cystic Teratoma) Ovary.- Evidence Favor a Postmeiotic (Parthenogenic) Cysts.- Testis.- Application Techniques Tumors Pineal Gland (and Its Environs).- Mediastinum.- Gland, Mediastinum, Region Neonatal Period Infancy.- Observations on Individuals Who Have with Sex Chromosome X Differentiation, Barr Body Formation, Discussion.- 4 Epidemiology Frequency.- Presacral Renal Intraspinal Thyroid Cervical Nasopharyngeal Cardiac, Gastric, Orbital, Hepatic, Uterine Conclusions.- 5 Malignant Alteration Benign Squamous Age Incidence.- Symptoms.- Gross Pathology.- Histology.- Spread.- Diagnosis Treatment.- Prognosis.- Carcinoid.- Adenocarcinoma.- Melanoma.- Sarcoma.- Miscellaneous Etiology Pathogenesis Alteration.- Extraovarian 6 Metastasis Incidence Natural Metastasis.- Data.- Patterns Metastases.- Effect Chemotherapy 7 Neural Tissues Frequency Nervous Tissue Types Neuroectodermal Present Fetal Structures Mature Reactive Phenomena Tissue.- Implants Neurogenic Metastases Ultrastructural Findings Clinicopathological Significance 8 Biological Markers Seminoma.- Immunocytochemical Approach.- Localization Placental Proteins.- Chorionic Gonadotropin (HCG).- Other Yolk Sac Differentiation.- Alphafetoprotein (AFP).- Products.- Fibronectin.- Carcinoembryonic Antigen (CEA).- Epithelial Membrane (EMA).- Ferritin.- Lactate Dehydrogenase.- Devoid Distinct Markers.- Radioimmunolocalization.- Multiple 9 Endocrine Aspects Mechanisms Underlying Manifestations.- Syndromes.- Syndromes HCG Production.- Arising from Steroid Hormone Production Absence HCG.- Resembling Those Hyperfunction.- Carcinoid Syndrome.- Ectopic Secretion.- 10 Polypeptide Hormone-Producing Cells Neoplasms.- Carcinoids.- Mucinous Implications 11 VAB-6 Combination Disseminated Cancer Primary Adjuvant Regimen Resected Stage II-B Testis Cancer.- Concluding Remarks.- 12 In Vitro.- Lines Some Characteristics Lines.- Carcinoma Athymic Mice.- Cytogenetics.- Virus by EC Cells.- Conclusion.- 13 Derived Teratoma Xenograft Teratocarcinoma Established Biochemical Properties.- Major Histocompatibility Antigens.- Embryonic SSEA-3.- Alkaline Phosphatase (ALP).- 14 Human-Mouse Hybrids: A Tool for Analysis Gene Activity Development.- Microcell Conventional Hybrids.- Induction Differentiation Reexpression Malic Enzyme MCP-6 PCG Expression HLA-A,B,C MCP-6.- X-Inactivation Using Genetics.- Isolation Developmentally Regulated DNA Sequences.- Summary 15 Mouse Teratocarcinoma: Model Teratocarcinoma?.- Teratocarcinoma.- Nature Stem Regulation Teratocarcinogenesis.- Comparison ECC.- References.