作者: Laizhong Chen , Jing Li , Lupei Du , Minyong Li
DOI: 10.1002/MED.21316
关键词:
摘要: Peptidases, which can cleave specific peptide bonds in innumerable categories of substrates, usually present pivotal positions protein activation, cell signaling and regulation as well the origination amino acids for generation or application other metabolic pathways. They are also involved many pathological conditions, such cancer, atherosclerosis, arthritis, neurodegenerative disorders. This review article aims to conduct a wide-ranging survey on development small-molecule fluorescent probes peptidases, realize state art tailor-made diverse types peptidases.