The Culture of Carbapenem Overconsumption: Where Does It Begin? Results of a Single-Center Survey.

摘要: Purpose: The United States has seen an increased consumption of carbapenem antibiotics in recent years. utilization these agents potential negative consequences, including the increasing incidence carbapenem-resistant Enterobacteriaceae. Reasons for rise use among providers acute care hospitals are not well elucidated literature. objectives this study were to identify factors that influence empiric a single academic medical center, and assess therapeutic knowledge pertaining use. Methods: A cross-sectional, single-center, 9-item electronic research survey was developed independently validated by infectious diseases pharmacist physician. distributed email accounts at center. Demographic data, affecting prescription, baseline assessed. Results: Ninety-five 416 responded (response rate 22.8%). Respondents across all levels training with primary roles internal medicine surgery. most important influencing suspected pathogens site infection, drug allergies, history multidrug resistant organisms, severity illness, type local resistance rates. recommendation from selected as likely factor deterring Misconceptions penicillin allergy beta-lactam cross reactivity, rates according institutional antibiogram, comparative efficacy data carbapenems apparent training. Conclusions: Provider misconceptions regarding several appear contribute unnecessary carbapenems. An opportunity exists hospital pharmacists improve prescribing patterns correcting provider through education.