Autosomal dominant polycystic kidney disease.

摘要: #### What you need to know Polycystic kidney disease (PKD) is an inherited condition defined by the pathological development of fluid-filled cysts throughout kidneys leading organ enlargement (fig 1⇓) and chronic disease. Autosomal dominant polycystic (ADPKD) commonest disease1 fourth cause failure worldwide.2 recessive PKD a rare usually identified antenatally or during neonatal period enlarged echogenic on ultrasound.3 This review will focus ADPKD. Fig 1  Anatomical illustration (right) compared with normal (left) #### Sources selection criteria I searched PubMed, Clinical Evidence, Cochrane Library for primary articles available in English until October 2015. Articles included systematic reviews, randomised clinical trials, observational studies. The following search terms were used isolation combination: “ADPKD,” “polycystic disease,” “progression,” “treatment,” “humans,” “complications,” “mutations.” I additional references from my personal archive. Where evidence based medicine was not available, published expert opinion referenced. ADPKD presents variety doctors more prevalent than combination …